MULTI-TISSUE TRANSCRIPTOME ANALYSIS OF TWO BEGONIA SPECIES REVEALS DYNAMIC PATTERNS OF EVOLUTION IN THE CHALCONE SYNTHASE GENE FAMILY

Multi-tissue transcriptome analysis of two Begonia species reveals dynamic patterns of evolution in the chalcone synthase gene family

Abstract Begonia is an important horticultural plant group, as well as one of the most speciose Angiosperm genera, with over 2000 described species.Genus wide studies of genome size have shown that Begonia has a highly variable genome size, and 22 k light ride analysis of paralog pairs has previously suggested that Begonia underwent a whole genome

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Suppression of Ribosome Biogenesis by Targeting WD Repeat Domain 12 (WDR12) Inhibits Glioma Stem-Like Cell Growth

Glioma stem-like cells (GSCs) are a subset of tumor cells that initiate malignant growth and promote the therapeutic resistance of glioblastoma, the most lethal primary brain tumor.Ribosome biogenesis is an essential cellular process to maintain cell growth, but its regulatory mechanism in GSCs remains largely unknown.Here, we show that WD repeat d

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Directional Selection of Microbial Community Reduces Propionate Accumulation in Glycerol and Glucose Anaerobic Bioconversion Under Elevated pCO2

Volatile fatty acid accumulation is a sign of digester perturbation.Previous work showed the thermodynamic limitations of hydrogen and CO2 in syntrophic propionate oxidation under elevated partial pressure of CO2 (pCO2).Here we study the effect of directional selection under increasing substrate load as a strategy to restructure the microbial commu

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WD40 domain divergence is important for functional differences between the fission yeast Tup11 and Tup12 co-repressor proteins.

We have previously demonstrated that subsets of Ssn6/Tup target genes have distinct requirements for the Schizosaccharomyces pombe homologs of the Tup1/Groucho/TLE co-repressor proteins, Tup11 and Tup12.The pentavite chewables very high level of divergence in the histone interacting repression domains of the two proteins suggested that determinants

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Transcript Profiles of Blumeria graminis Development During Infection Reveal a Cluster of Genes That Are Potential Virulence Determinants

High-density cDNA microarrays (2,027 unigenes) were used to analyze transcript profiles of the plant-pathogenic fungus Blumeria graminis f.sp.hordei throughout its asexual life cycle and development of infection.RNA was obtained from four stages preceding penetration and four stages after penetration of the host cells.The microarray data was valida

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